About this archive

This is a static copy of ltx.life, the website of Lowell Therapeutics, Inc. — a Lowell, Massachusetts company that developed Niyad™, an investigational regional anticoagulant for the dialysis circuit. The pages are the company’s own markup and wording, captured by the Internet Archive on 9 May 2021 and rebuilt here to run from a folder or a web server without WordPress.

Lowell Therapeutics no longer operates independently: its assets were acquired by AcelRx Pharmaceuticals in January 2022. This site is an independent archive of the company’s published material, not an official site, and it is not affiliated with the company or its successor. See What happened next below.

What was recovered

  • Twelve pages — the landing page, Our Opportunity, Niyad™, Meet Lowell, Investors, the News listing and six news posts.
  • The theme and page styling — Flatsome 3.13’s stylesheet and the page-specific CSS the site generated, kept as they were.
  • The landing-page composite image, the “iron” line icon and the favicons, downloaded from the archive of the site’s own media library.
  • Two photographs the site had used (a surgeon in theatre, and a pair of hands at a bedside). Their file names carried the Unsplash identifiers, so the originals were retrieved from the Unsplash CDN.
  • The corporate presentation PDF that the Investors page linked to (9 August 2021).
  • The wording of every page — team biographies, product copy, the news posts and the contact form labels are reproduced as published.

What was replaced, and why

Most of the media library was never archived. Where an original was missing, a replacement is used and recorded here; nothing is presented as the company’s own photograph when it is not.

AssetWhat is here now
Laboratory photograph (laboratory-2815641_1920.jpg, a Pixabay file) Replacement: “Lab technician holds a tray of sealed test tubes”, photograph by Shixart1985, Wikimedia Commons, CC BY 2.0.
Background photograph on Meet Lowell (photo-1542736667-069246bdbc6d) The Unsplash file has since been removed. Replacement: “Scientist in laboratory”, photograph by Milla Talassalo, Wikimedia Commons, CC BY-SA 4.0.
Niyad™ circuit diagram (DIAGRAM.png, made for the site) Redrawn as an SVG for this archive from the page’s own description: blood leaves the patient, passes the pump and the Niyad™ infusion point, is filtered, and returns; dialysate and effluent are shown separately.
Decorative flow background (BGFLOW.png) Redrawn as a soft SVG pattern in the same teal.
Line icons for patient, surgeon, flag, chart and gear Redrawn as SVGs in the style of the one icon that survived (the “iron” icon).
Portraits of James Wilkie, Elaine Liong, Michelle Merrigan, Stuart Goldstein, John Kellum and Kathleen Liu Not archived. Each card shows the person’s initials instead; no stand-in photograph of a different person is used.
The Flatsome icon font (fl-icons.woff2) Missing from the archive; arrows, the menu button and the social marks are drawn with CSS and small inline SVGs.
Google Fonts (Baskervville, Raleway) Downloaded and served from assets/font/ so the pages make no third-party request.

What was changed

  • WordPress was removed. jQuery, the theme scripts, the emoji loader and the analytics were stripped; what remains is HTML, CSS and about 60 lines of JavaScript.
  • The mobile menu, back-to-top button and contact-form guard were rebuilt (assets/js/site.js) because the theme provided them with JavaScript.
  • Sections that the theme faded in on scroll were marked as visible, so the content does not depend on a script to appear.
  • Template furniture was removed: the comment threads and reply forms, the “Recent Comments” widget (which still contained the WordPress sample comment), the search box, the share row that pointed at the retired domain, the author box with its Gravatar image, and the form-processor hidden fields.
  • The contact form does not submit. There is no server behind this copy; the form is shown as published and says so.
  • The News page is the site’s category archive (/category/news/), because the empty /news/ page contained no posts.

What happened next

The archive predates the company’s exit. From public filings:

  • On 14 November 2021 AcelRx Pharmaceuticals agreed to acquire Lowell Therapeutics in a transaction valued at approximately $32.5 million plus net cash, including up to about $26.0 million of contingent consideration tied to regulatory and sales milestones.
  • The merger closed on 7 January 2022. AcelRx accounted for it as an asset acquisition, with substantially all of the value concentrated in Lowell’s intellectual property — Niyad™ and LTX-608.
  • AcelRx later became Talphera, Inc., which still lists Niyad® for continuous renal replacement therapy in its pipeline. See talphera.com.

Sources: AcelRx 8-K dated 15 November 2021 (including the release “AcelRx Pharmaceuticals to Acquire Lowell Therapeutics”), AcelRx 8-K dated 12 January 2022 (closing and CVR agreement), AcelRx 10-K for 2021, and Lowell Therapeutics’ three Form D filings of 2021.

Rights

The design, the wording, the Lowell Therapeutics™ name, Niyad™ and the company’s own photographs belong to Lowell Therapeutics, Inc. or its successor. This archive is a reference copy, not an official site, and it is not affiliated with the company. Where a replacement image is used its photographer and licence are named above. The two Unsplash photographs are used under the Unsplash licence; the archive did not record the photographers’ names, and the Unsplash CDN does not expose them for a bare image request.

Captured 9 May 2021; this rebuild compiled in November 2026. Pages are reproduced as published at that time.